GTX85150
Pappalysin 2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85150
- Zusätzliche Namen:
- pappalysin 2 , PAPP-A2 , PAPP-E , PAPPE , PLAC3
- Anwendung:
- ELISA, WB, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- PLAC3 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human PLAC3.The immunogen is located within amino acids 450 - 500 of PLAC3.
- Uniprot:
- Q9BXP8
- Synonyme:
- PAPP-A2;PAPP-E;pappalysin-2;PAPPE;PLAC3;placenta-specific 3;pregnancy-associated plasma preproprotein-A2;Pregnancy-associated plasma protein A2;pregnancy-associated plasma protein E1;SSDA
- Weitere Details:
- PLAC3 (placenta-specific protein 3), also known as PAPP-A2, is a metalloproteinase that cleaves the insulin-like growth factor-binding protein (IGFBP)-5 in a IGF-independent fashion. It has been suggested that the cleavage of IGFBP-5 and to a lesser extent IGFBP-3 produced in the maternal decidua promotes feto-placental growth. Recent studies have shown elevated levels of PLAC3 in hypertensive disorders of pregnancy including preeclampsia and HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome.
- Versandbedingungen:
- Blue Ice