GTX85146
MFSD2B antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85146
- Zusätzliche Namen:
- major facilitator superfamily domain containing 2B
- Anwendung:
- ELISA, WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- MFSD2B antibody was raised against a 15 amino acid synthetic peptide near the center of human MFSD2B.The immunogen is located within amino acids 240 - 290 of MFSD2B.
- Uniprot:
- A6NFX1
- Synonyme:
- hMfsd2b;major facilitator superfamily domain-containing protein 2B;S1P transporter;SLC59A2;sphingosine 1-phosphate transporter
- Weitere Details:
- Multidrug transporters, such as MFSD2B, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs. Major Facilitator Superfamily (MFS) members are capable of transporting various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific. MFSD2B is closely related to MFSD2A, which is expressed in many tissues and is highly induced in liver and brown adipose tissue (BAT) during fasting, playing a major role in the induction of MFSD2A expression during adaptive thermogenesis. Unlike MFSD2A, MFSD2B is expressed in few tissues and at relatively low levels, and is not induced during fasting, suggesting that MFSD2B may play other roles.
- Versandbedingungen:
- Blue Ice