GTX85143
EFCAB4A antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85143
- Zusätzliche Namen:
- calcium release activated channel regulator 2B , EFCAB4A
- Anwendung:
- ELISA, WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- EFCAB4A antibody was raised against a 15 amino acid synthetic peptide near the center of human EFCAB4A.The immunogen is located within amino acids 290 - 340 of EFCAB4A.
- Uniprot:
- Q8N4Y2
- Synonyme:
- Ca2+ release-activated Ca2+ (CRAC) channel regulator 2B;calcium release-activated calcium channel regulator 2B;Calcium release-activated channel regulator 2B;CRAC channel regulator 2B;CRAC regulator 2B;EF-hand calcium binding domain 4A;EF-hand calcium-binding domain-containing protein 4A;EFCAB4A
- Weitere Details:
- EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the detailed function is still under investigation. It is likely to play a similar role as the related protein EFCAB4B, which acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration.
- Versandbedingungen:
- Blue Ice