GTX85134
SLC39A2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85134
- Zusätzliche Namen:
- solute carrier family 39 member 2 , 6A1 , ETI-1 , ZIP-2 , ZIP2
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- ZIP2 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human ZIP2.The immunogen is located within amino acids 70 - 120 of ZIP2.
- Uniprot:
- Q9NP94
- Synonyme:
- 6A1;ETI-1;solute carrier family 39 (zinc transporter), member 2;Solute carrier family 39 member 2;zinc transporter ZIP2;zinc uptake transporter 2;ZIP-2;ZIP2;Zrt- and Irt-like protein 2
- Weitere Details:
- The zinc transporter ZIP2, also known as SLC39A2, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP3, ZIP2- mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.
- Versandbedingungen:
- Blue Ice