GTX85133
ZIP3 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85133
- Zusätzliche Namen:
- solute carrier family 39 member 3 , ZIP-3 , ZIP3
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- ZIP3 antibody was raised against a 16 amino acid synthetic peptide near the center of human ZIP3.The immunogen is located within amino acids 110 - 160 of ZIP3.
- Uniprot:
- Q9BRY0
- Synonyme:
- solute carrier family 39 (zinc transporter), member 3;Solute carrier family 39 member 3;zinc transporter ZIP3;ZIP-3;ZIP3;zrt- and Irt-like protein 3
- Weitere Details:
- The zinc transporter ZIP3, also known as SLC39A3, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP2, ZIP3- mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.
- Versandbedingungen:
- Blue Ice