GTX85131
SLC39A6 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85131
- Zusätzliche Namen:
- solute carrier family 39 member 6 , LIV-1 , ZIP6
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- SLC39A6 antibody was raised against a 16 amino acid synthetic peptide near the center of human SLC39A6.The immunogen is located within amino acids 430 - 480 of SLC39A6.
- Uniprot:
- Q13433
- Synonyme:
- estrogen-regulated protein LIV-1;LIV-1;LIV-1 protein, estrogen regulated;LIV1;solute carrier family 39 (metal ion transporter), member 6;solute carrier family 39 (zinc transporter), member 6;Solute carrier family 39 member 6;zinc transporter ZIP6;ZIP-6;ZIP6;zrt- and Irt-like protein 6
- Weitere Details:
- The zinc transporter ZIP6, also known as SLC39A6, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP6 was initially identified as LIV-1, an estrogen-regulated gene that has been implicated in metastatic breast cancer. Elevated ZIP6 expression has also been reported in human cervical cancer and the HeLa cell line; down-regulation of ZIP6 expression in HeLa by RNAi inhibited cell proliferation, colony formation, migration and invasiveness, as well as decreasing Snail and Slug levels, suggesting ZIP6 plays a regulatory role on the ERK1/2-Snail/Slug pathway.
- Versandbedingungen:
- Blue Ice