MD2 antibody [9F1B1]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX85122
Zusätzliche Namen:: lymphocyte antigen 96 , ESOP-1 , MD-2 , MD2 , ly-96
Anwendung:: ELISA, WB, IHC-P
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human, Mouse
Buffer:: PBS, 0.02% Sodium azide.
Immunogen:: Mouse monoclonal MD-2 antibody was raised against a recombinant protein corresponding to amino acids 2 to 160 of human MD-2.
Klon:: 9F1B1
Uniprot:: Q9Y6Y9
Synonyme:: ESOP-1;ly-96;lymphocyte antigen 96;MD-2;MD2;myeloid differentiation protein-2;protein MD-2
Weitere Details:: MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2; e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.

Versandbedingungen:: Blue Ice