GTX85104
SIRT5 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85104
- Zusätzliche Namen:
- sirtuin 5 , SIR2L5
- Anwendung:
- ELISA, WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Chicken/Avian
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- SIRT5 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human SIRT5.The immunogen is located within the last 50 amino acids of SIRT5.
- Uniprot:
- Q9NXA8
- Synonyme:
- NAD-dependent deacetylase sirtuin-5;NAD-dependent lysine demalonylase and desuccinylase sirtuin-5, mitochondrial;NAD-dependent protein deacylase sirtuin-5, mitochondrial;Regulatory protein SIR2 homolog 5;silent mating type information regulation 2, S.cerevisiae, homolog 5;sir2-like 5;SIR2-like protein 5;SIR2L5;sirtuin type 5
- Weitere Details:
- The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT5 localizes to mitochondria, deacetylates carbamoyl phosphate synthetase 1, and is involved in the regulation of the urea cycle.
- Versandbedingungen:
- Blue Ice