GTX85103
SIRT7 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85103
- Zusätzliche Namen:
- sirtuin 7 , SIR2L7
- Anwendung:
- ELISA, WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Chicken/Avian
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- SIRT7 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human SIRT7.The immunogen is located within amino acids 50 - 100 of SIRT7.
- Uniprot:
- Q9NRC8
- Synonyme:
- NAD-dependent deacetylase sirtuin-7;NAD-dependent protein deacetylase sirtuin-7;NAD-dependent protein deacylase sirtuin-7;regulatory protein SIR2 homolog 7;silent mating type information regulation 2, S.cerevisiae, homolog 7;SIR2-like protein 7;sir2-related protein type 7;SIR2L7;sirtuin type 7
- Weitere Details:
- The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT7 is a nucleolar protein that positively regulates RNA polymerase I transcription and has been postulated to enable cells to sustain critical functions by inhibiting cell growth under severe stress conditions.
- Versandbedingungen:
- Blue Ice