GTX85067
TIM-1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85067
- Zusätzliche Namen:
- hepatitis A virus cellular receptor 1 , CD365 , HAVCR , HAVCR-1 , KIM-1 , KIM1 , TIM , TIM-1 , TIM1 , TIMD-1 , TIMD1
- Anwendung:
- ELISA, WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- TIM-1 antibody was raised against a 16 amino acid synthetic peptide from near the center of human TIM-1.The immunogen is located within amino acids 230 - 280 of TIM-1.
- Uniprot:
- Q96D42
- Synonyme:
- CD365;HAVCR;HAVCR-1;hepatitis A virus cellular receptor 1;kidney injury molecule 1;KIM-1;KIM1;T cell immunoglobin domain and mucin domain protein 1;T-cell immunoglobulin and mucin domain-containing protein 1;T-cell immunoglobulin mucin family member 1;T-cell immunoglobulin mucin receptor 1;T-cell membrane protein 1;TIM;TIM-1;TIM1;TIMD-1;TIMD1
- Weitere Details:
- The human form of TIM-1 was initially discovered as a membrane glycoprotein through which the hepatitis A virus can gain entry into a cell. It was also identified as kidney injury molecule 1 (Kim-1), a predicted adhesion molecule that is upregulated on the surfaces of kidney epithelia. It is also expressed on T helper 2 (Th2) cells of the immune system, and following the binding of its natural ligand TIM-4, stimulates T cell expansion and cytokine production in response to viral challenge. It has been suggested that hyperactivation of TIM-1 leads to an increased level of Th2 responsiveness and asthma susceptibility, and antibodies to TIM-1 may therefore be a novel approach to treating asthma.
- Versandbedingungen:
- Blue Ice