GTX85040
FGF4 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85040
- Zusätzliche Namen:
- fibroblast growth factor 4 , FGF-4 , HBGF-4 , HST , HST-1 , HSTF-1 , HSTF1 , K-FGF , KFGF
- Anwendung:
- ELISA, WB, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- FGF4 antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of the human FGF4.The immunogen is located within the last 50 amino acids of FGF4.
- Uniprot:
- P08620
- Synonyme:
- FGF-4;fibroblast growth factor 4;HBGF-4;heparin secretory transforming protein 1;Heparin secretory-transforming protein 1;heparin-binding growth factor 4;HST;HST-1;HSTF-1;HSTF1;human stomach cancer, transforming factor from FGF-related oncogene;K-FGF;kaposi sarcoma oncogene;KFGF;oncogene HST;transforming protein KS3
- Weitere Details:
- Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities and play key roles in growth and survival of stem cells during embryogenesis, tissue regeneration, and carcinogenesis. FGF4 was identified by its strong oncogenic transforming activity and is a potent angiogenic factor, expressed in several highly vascularized tumors and also in adult mouse testis, intestine, and brain. Studies on the mouse homolog suggests a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. Furthermore, FGF4 regulates neural progenitor cell proliferation and neuronal differentiation. Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells and a putative feedback inhibition mechanism by a novel FGF4 splice isoform that may serve to promote differentiation at a later stages of development.
- Versandbedingungen:
- Blue Ice