GTX85028
NENF antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85028
- Zusätzliche Namen:
- neudesin neurotrophic factor , CIR2 , SCIRP10 , SPUF
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- NENF antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human NENF.The immunogen is located within the last 50 amino acids of NENF.
- Uniprot:
- Q9UMX5
- Synonyme:
- cell growth-inhibiting protein 47;cell immortalization-related protein 2;CIR2;neudesin;neuron-derived neurotrophic factor;Protein GIG47;SCIRP10;SCIRP10-related protein;secreted protein of unknown function;Spinal cord injury related protein 10;SPUF
- Weitere Details:
- NENF is a secreted protein that is expressed in neurons but not glial cells of the brain. This protein has neurotrophic activity in primary cultured mouse neurons but not mitogenic activity in primary cultured mouse astrocytes. NENF activated mitogen-activated protein (MAP) and phosphotidylinositol-3 kinase pathways and could be inhibited by pertussis toxin but not receptor tyrosine kinases, suggesting that NENF acts through a Gi/Go-protein-coupled receptor. Despite its predicted molecular weight of ~20kDa, NENF is observed at 37kDa in SDS-PAGE.
- Versandbedingungen:
- Blue Ice