GTX85004
FREM2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85004
- Zusätzliche Namen:
- FRAS1 related extracellular matrix protein 2 , FRASRS2
- Anwendung:
- ELISA, WB, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- FREM2 antibody was raised against a 19 amino acid synthetic peptide near the center of human FREM2.The immunogen is located within amino acids 1920 - 1970 of FREM2.
- Uniprot:
- Q5SZK8
- Synonyme:
- CRYPTOP;ECM3 homolog;FRAS1 related extracellular matrix protein 2;FRAS1-related extracellular matrix protein 2;FRASRS2
- Weitere Details:
- FREM2 is a member of the FRAS1-related extracellular matrix protein family and like FREM1, mutations in the FREM2 gene are associated with Fraser syndrome. FREM2 localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes and is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia. The FREM2 gene is one of several genes whose transcription is affecteded by TFAP2C, a transcription factor involved in mammary development, differentiation, and oncogenesis.
- Versandbedingungen:
- Blue Ice