GTX85003
ATP11B antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85003
- Zusätzliche Namen:
- ATPase phospholipid transporting 11B (putative) , ATPIF , ATPIR
- Anwendung:
- ELISA, WB, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- ATP11B antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human ATP11B.The immunogen is located within amino acids 290 - 340 of ATP11B.
- Uniprot:
- Q9Y2G3
- Synonyme:
- ATPase class VI type 11B;ATPase IR;ATPase, class VI, type 11B;ATPIF;ATPIR;P4-ATPase flippase complex alpha subunit ATP11B;phospholipid-transporting ATPase IF;probable phospholipid-transporting ATPase IF;truncated ATPase 11B protein
- Weitere Details:
- ATP11B is a widely expressed integral membrane ATPase and is thought to drive the transport of phospholipids across membranes. It has been suggested that ATP11B is hormonally regulated and plays a role in the subnuclear trafficking of transcription factors with RING motifs. While the exact molecule ATP11B transports is unknown, increased mRNA expression of the homologous ATP11A has been observed in cells resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting that ATP11B may also play a role in cell survival under harsh conditions.
- Versandbedingungen:
- Blue Ice