GTX85000
SH3RF2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX85000
- Zusätzliche Namen:
- SH3 domain containing ring finger 2 , HEPP1 , POSHER , PPP1R39 , RNF158
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- SH3RF2 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human SH3RF2.The immunogen is located within the last 50 amino acids of SH3RF2.
- Uniprot:
- Q8TEC5
- Synonyme:
- E3 ubiquitin-protein ligase SH3RF2;heart protein phosphatase 1-binding protein;HEPP1;phosphatase 1 binding protein;POSH-eliminating RING protein;POSHER;PPP1R39;protein phosphatase 1 regulatory subunit 39;putative E3 ubiquitin-protein ligase SH3RF2;RING finger protein 158;RING-type E3 ubiquitin transferase SH3RF2;RNF158;SH3 domain-containing RING finger protein 2
- Weitere Details:
- Although the SH3 domain containing ring finger 2 protein (SH3RF2) has been identified as a marker of the nucleus accumbens in the human brain, little is known about this protein. Recent yeast two-hybrid experiments have shown that SH3RF2 associates with protein phosphatase 1 (PP1) and is expressed primarily in heart and testis tissue. Recombinant SH3RF2 enhanced PP1 enzymatic activity and antagonized the ability of phopho-inhibitor-1 or -2 to inhibit PP1, suggesting that SH3RF2 may play a role working with PP1 in cardiac functions.
- Versandbedingungen:
- Blue Ice