GTX84997
TCF12 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX84997
- Zusätzliche Namen:
- transcription factor 12 , CRS3 , HEB , HTF4 , HsT17266 , TCF-12 , bHLHb20 , p64
- Anwendung:
- ELISA, WB, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- TCF12 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human TCF12.The immunogen is located within amino acids 50 - 100 of TCF12.
- Uniprot:
- Q99081
- Synonyme:
- bHLHb20;class B basic helix-loop-helix protein 20;CRS3;DNA-binding protein HTF4;E-box-binding protein;HEB;helix-loop-helix transcription factor 4;HsT17266;HTF4;p64;TCF-12;transcription factor 12;transcription factor HTF-4
- Weitere Details:
- TCF12, also known as HTF4, is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. TCF12 is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. TCF12, in combination with E2A, is required to block thymocyte proliferation prior to pre-TCR expression and is critical for proper T cell differentiation. Recent reports have shown that TCF12 is also a critical factor required for the development of invariant natural killer T cells.
- Versandbedingungen:
- Blue Ice