BTK antibody [12H4]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX84792
Zusätzliche Namen:: Bruton tyrosine kinase , AGMX1 , AT , ATK , BPK , IGHD3 , IMD1 , PSCTK1 , XLA
Anwendung:: Flow Cytometry, WB, IHC-P, IF, ICC
Konzentration:: 0.92 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Full length human recombinant protein of human BTK (NP_000052) produced in HEK293T cell.
Klon:: 12H4
Uniprot:: Q06187
Synonyme:: agammaglobulinaemia tyrosine kinase;Agammaglobulinemia tyrosine kinase;AGMX1;AT;ATK;B-cell progenitor kinase;BPK;Bruton agammaglobulinemia tyrosine kinase;Bruton tyrosine kinase;Bruton's tyrosine kinase;dominant-negative kinase-deficient Brutons tyrosine kinase;IGHD3;IMD1;PSCTK1;truncated Bruton agammaglobulinemia tyrosine kinase;tyrosine-protein kinase BTK;XLA
Weitere Details:: Plays a crucial role in B-cell ontogeny. Transiently phosphorylates GTF2I on tyrosine residues in response to B-cell receptor cross-linking. Required for the formation of functional ARID3A DNA-binding complexes.