FADD antibody [1C11]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX84542
Zusätzliche Namen:: Fas associated via death domain , GIG3 , MORT1
Anwendung:: Flow Cytometry, WB
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Full length human recombinant protein of human FADD (NP_003815) produced in HEK293T cell.
Klon:: 1C11
Uniprot:: Q13158
Synonyme:: Fas (TNFRSF6)-associated via death domain;FAS-associated death domain protein;Fas-associating death domain-containing protein;Fas-associating protein with death domain;GIG3;growth-inhibiting gene 3 protein;Mediator of receptor induced toxicity;mediator of receptor-induced toxicity;MORT1;Protein FADD
Weitere Details:: Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.