Glucokinase antibody [3E3]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX84440
Zusätzliche Namen:: glucokinase , FGQTL3 , GK , GLK , HHF3 , HK4 , HKIV , HXKP , LGLK , MODY2
Anwendung:: WB, IHC-P, IF, ICC
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Full length human recombinant protein of human GCK (NP_000153) produced in HEK293T cell.
Klon:: 3E3
Uniprot:: P35557
Synonyme:: ATP:D-hexose 6-phosphotransferase;FGQTL3;GK;GLK;glucokinase (hexokinase 4);hexokinase D, pancreatic isozyme;hexokinase type IV;hexokinase-4;Hexokinase-D;HHF3;HK IV;HK4;HKIV;HXKP;LGLK;MODY2;PNDM1
Weitere Details:: Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Glucokinase has a high Km for glucose, and so it is effective only when glucose is abundant. The role of GCK is to provide G6P for the synthesis of glycogen. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage.