MAD2L1 antibody [4D2]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX84169
Zusätzliche Namen:: mitotic arrest deficient 2 like 1 , HSMAD2 , MAD2
Anwendung:: WB, IF, ICC
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Full length human recombinant protein of human MAD2L1 (NP_002349) produced in HEK293T cell.
Klon:: 4D2
Uniprot:: Q13257
Synonyme:: HSMAD2;MAD2;MAD2 (mitotic arrest deficient, yeast, homolog)-like 1;MAD2 mitotic arrest deficient-like 1;MAD2-like protein 1;mitotic arrest deficient 2-like protein 1;mitotic arrest deficient, yeast, homolog-like 1;mitotic spindle assembly checkpoint protein MAD2A
Weitere Details:: Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.