NSE2 antibody [4H9]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX83996
Zusätzliche Namen:: NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase , C8orf36 , MMS21 , NSE2 , ZMIZ7
Anwendung:: Flow Cytometry, WB, IF, ICC
Konzentration:: 0.81 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Full length human recombinant protein of human NSMCE2 (NP_775956) produced in E.coli.
Klon:: 4H9
Uniprot:: Q96MF7
Synonyme:: C8orf36;E3 SUMO-protein ligase NSE2;E3 SUMO-protein transferase NSE2;methyl methanesulfonate sensitivity gene 21;MMS21;MMS21 homolog;non-SMC element 2, MMS21 homolog;non-structural maintenance of chromosomes element 2 homolog;NSE2;NSMCE2/PVT1 fusion;PVT1/NSMCE2 fusion;zinc finger, MIZ-type containing 7;ZMIZ7
Weitere Details:: E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair.

Versandbedingungen:: Blue Ice