NUMB antibody [1A7]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX83974
Zusätzliche Namen:: NUMB endocytic adaptor protein , C14orf41 , S171 , c14_5527
Anwendung:: Flow Cytometry, WB, IF, ICC
Konzentration:: 0.6 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Canine, Human
Buffer:: PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Full length human recombinant protein of human NUMB (NP_003735) produced in HEK293T cell.
Klon:: 1A7
Uniprot:: P49757
Synonyme:: c14_5527;C14orf41;h-Numb;numb homolog;protein numb homolog;Protein S171;S171
Weitere Details:: Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.