PDX1 antibody [5D5]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX83918
Zusätzliche Namen:: pancreatic and duodenal homeobox 1 , GSF , IDX-1 , IPF1 , IUF1 , MODY4 , PAGEN1 , PDX-1 , STF-1
Anwendung:: WB
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Full length human recombinant protein of human PDX1 (NP_000200) produced in E.coli.
Klon:: 5D5
Uniprot:: P52945
Synonyme:: glucose-sensitive factor;GSF;IDX-1;Insulin promoter factor 1;insulin promoter factor 1, homeodomain transcription factor;insulin upstream factor 1;IPF-1;IPF1;islet/duodenum homeobox-1;IUF-1;IUF1;MODY4;PAGEN1;pancreas/duodenum homeobox protein 1;pancreatic-duodenal homeobox factor 1;PDX-1;somatostatin transcription factor 1;somatostatin-transactivating factor 1;STF-1
Weitere Details:: Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell.

Versandbedingungen:: Blue Ice