RALBP1 antibody [11B2]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX83728
Zusätzliche Namen:: ralA binding protein 1 , RIP1 , RLIP1 , RLIP76
Anwendung:: Flow Cytometry, WB, IF, ICC, IP
Konzentration:: 0.84 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Canine, Human, Rat
Buffer:: PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Full length human recombinant protein of human RALBP1 (NP_006779) produced in HEK293T cell.
Klon:: 11B2
Uniprot:: Q15311
Synonyme:: 76 kDa Ral-interacting protein;dinitrophenyl S-glutathione ATPase;DNP-SG ATPase;ral-interacting protein 1;ralA-binding protein 1;RIP1;RLIP1;RLIP76
Weitere Details:: Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.

Versandbedingungen:: Blue Ice