RPA32 antibody [7C12]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX83695
Zusätzliche Namen:: replication protein A2 , REPA2 , RP-A p32 , RP-A p34 , RPA32
Anwendung:: Flow Cytometry, WB, IHC-P, IF, ICC, IP
Konzentration:: 0.75 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Canine, Human
Buffer:: PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Full length human recombinant protein of human RPA2 (NP_002937) produced in HEK293T cell.
Klon:: 7C12
Uniprot:: P15927
Synonyme:: REPA2;replication factor A protein 2;replication protein A 32 kDa subunit;replication protein A 34 kDa subunit;RF-A protein 2;RP-A p32;RP-A p34;RPA32
Weitere Details:: Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair | it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.

Versandbedingungen:: Blue Ice