alpha 1 Antitrypsin antibody [11G2]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX83663
Zusätzliche Namen:: serpin family A member 1 , A1A , A1AT , AAT , PI , PI1 , PRO2275 , alpha1AT , nNIF
Anwendung:: WB, IHC-P, IP
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Canine, Human
Buffer:: PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Full-length protein expressed in 293T cell transfected with human SERPINA1 expression vector
Klon:: 11G2
Uniprot:: P01009
Synonyme:: A1A;A1AT;AAT;alpha-1 antitrypsin;alpha-1 protease inhibitor;alpha-1 proteinase inhibitor;alpha-1-antiproteinase;alpha-1-antitrypsin;alpha-1-antitrypsin short transcript variant 1C4;alpha-1-antitrypsin short transcript variant 1C5;alpha1AT;anti-elastase;epididymis secretory sperm binding protein;nNIF;PI;PI1;PRO2275;protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin;serine (or cysteine) proteinase inhibitor, clade A, member 1;serpin A1;serpin peptidase inhibitor clade A (alpha-1antiproteinase, antitrypsin) member 1;serpin peptidase inhibitor clade A member 1;serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
Weitere Details:: Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin. Short peptide from AAT (SPAAT) is a reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE).

Versandbedingungen:: Blue Ice