XRCC4 antibody [4H9]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX83406
Zusätzliche Namen:: X-ray repair cross complementing 4 , SSMED
Anwendung:: WB, IHC-P
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Full-length protein expressed in 293T cell transfected with human XRCC4 expression vector
Klon:: 4H9
Uniprot:: Q13426
Synonyme:: DNA repair protein XRCC4;SSMED;X-ray repair complementing defective repair in Chinese hamster cells 4;X-ray repair cross-complementing protein 4
Weitere Details:: Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.