CD10 antibody [2A1H5E1]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX83393
Zusätzliche Namen:: membrane metalloendopeptidase , CALLA , CD10 , CMT2T , NEP , SCA43 , SFE
Anwendung:: ELISA, IHC-P
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Unpurified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: Ascites, 0.03% Sodium azide.
Immunogen:: Purified recombinant fragment of human CD-10 expressed in E. Coli.
Klon:: 2A1H5E1
Uniprot:: P08473
Synonyme:: atriopeptidase;CALLA;CD10;CMT2T;common acute lymphocytic leukemia antigen;Enkephalinase;membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10);membrane metallo-endopeptidase variant 1;membrane metallo-endopeptidase variant 2;NEP;neprilysin;neprilysin-390;neprilysin-411;neutral endopeptidase 24.11;SCA43;SFE;skin fibroblast elastase
Weitere Details:: This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice