RTN3 antibody [1E11]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX83351
Zusätzliche Namen:: reticulon 3 , ASYIP , HAP , NSPL2 , NSPLII , RTN3-A1
Anwendung:: ELISA, IF, ICC
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Unpurified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: Ascites, 0.03% Sodium azide.
Immunogen:: Purified recombinant fragment of RTN3 expressed in E. Coli.
Klon:: 1E11
Uniprot:: O95197
Synonyme:: ASY interacting protein;ASYIP;HAP;homolog of ASY protein;neuroendocrine-specific protein-like 2;neuroendocrine-specific protein-like II;NSP-like protein 2;NSP-like protein II;NSPL2;NSPLII;reticulon-3;RTN3-A1
Weitere Details:: This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12. [provided by RefSeq, May 2012]

Versandbedingungen:: Blue Ice