Skip to content

Datenblatt ansehen

open_in_new
  1. Alles ansehen
  2. Monoclonal

GTX83349

Estrogen Receptor alpha antibody [2B7]

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX83349
Zusätzliche Namen:
estrogen receptor 1 , ER , ESR , ESRA , ESTRR , Era , NR3A1
Anwendung:
ELISA, WB, IHC-P
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Protein G Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Mouse
Reaktivitäten:
Human
Buffer:
PBS, 0.03% Sodium azide.
Immunogen:
Purified recombinant fragment of human ER-alpha (410-592aa) expressed in E. Coli.
Klon:
2B7
Uniprot:
P03372
Synonyme:
E2 receptor alpha;ER;ER-alpha;Era;ESR;ESRA;estradiol receptor;estrogen nuclear receptor alpha;estrogen receptor;estrogen receptor alpha E1-E2-1-2;estrogen receptor alpha E1-N2-E2-1-2;ESTRR;NR3A1;nuclear receptor subfamily 3 group A member 1;oestrogen receptor alpha
Weitere Details:
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]
Versandbedingungen:
Blue Ice