TrkC antibody [7H6]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX83321
Zusätzliche Namen:: neurotrophic receptor tyrosine kinase 3 , GP145-TrkC , TRKC , gp145(trkC)
Anwendung:: ELISA, WB, IHC-P
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Unpurified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: Ascites, 0.03% Sodium azide.
Immunogen:: Purified recombinant extracellular fragment of human TrkC (aa32-429) fused with hIgGFc tag expressed in HEK293 cells.
Klon:: 7H6
Uniprot:: Q16288
Synonyme:: ETS related protein-neurotrophic receptor tyrosine kinase fusion protein;ETV6-NTRK3 fusion;GP145-TrkC;gp145(trkC);Neurotrophic tyrosine kinase receptor type 3;neurotrophic tyrosine kinase, receptor, type 3;NT-3 growth factor receptor;TRKC;TrkC tyrosine kinase;tyrosine kinase receptor C
Weitere Details:: This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]

Versandbedingungen:: Blue Ice