Wnt1 antibody [10C8]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX83320
Zusätzliche Namen:: Wnt family member 1 , BMND16 , INT1 , OI15
Anwendung:: ELISA, Flow Cytometry, WB, IHC-P, IF, ICC
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Unpurified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human, Mouse
Buffer:: Ascites, 0.03% Sodium azide.
Immunogen:: Purified recombinant fragment of WNT1 expressed in E. Coli.
Klon:: 10C8
Uniprot:: P04628
Synonyme:: BMND16;INT1;OI15;proto-oncogene Int-1 homolog;proto-oncogene Wnt-1;wingless-type MMTV integration site family member 1;wingless-type MMTV integration site family, member 1 (oncogene INT1)
Weitere Details:: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region. [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice