MATK antibody [9D7]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX83311
Zusätzliche Namen:: megakaryocyte-associated tyrosine kinase , CHK , CTK , HHYLTK , HYL , HYLTK , Lsk
Anwendung:: ELISA, Flow Cytometry, WB
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Unpurified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: Ascites, 0.03% Sodium azide.
Immunogen:: Purified recombinant fragment of human MATK expressed in E. Coli.
Klon:: 9D7
Uniprot:: P42679
Synonyme:: CHK;CSK homologous kinase;Csk-homologous kinase;Csk-type protein tyrosine kinase;CTK;hematopoietic consensus tyrosine-lacking kinase;HHYLTK;hydroxyaryl-protein kinase;HYL;HYL tyrosine kinase;HYLTK;leukocyte carboxyl-terminal src kinase related;Lsk;megakaryocyte-associated tyrosine-protein kinase;protein kinase HYL;tyrosine kinase MATK;tyrosine-protein kinase CTK;tyrosylprotein kinase
Weitere Details:: The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice