BMAL1 antibody [1C5]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX83281
Zusätzliche Namen:: aryl hydrocarbon receptor nuclear translocator like , BMAL1 , BMAL1c , JAP3 , MOP3 , PASD3 , TIC , bHLHe5
Anwendung:: ELISA, WB, IHC-P
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Unpurified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: Ascites, 0.03% Sodium azide.
Immunogen:: Purified recombinant fragment of human BMAL1 expressed in E. Coli.
Klon:: 1C5
Uniprot:: O00327
Synonyme:: ARNT-like protein 1, brain and muscle;aryl hydrocarbon receptor nuclear translocator-like protein 1;basic helix-loop-helix family member e5;basic-helix-loop-helix-PAS orphan MOP3;basic-helix-loop-helix-PAS protein MOP3;bHLH-PAS protein JAP3;bHLHe5;BMAL1;BMAL1c;brain and muscle ARNT-like 1;class E basic helix-loop-helix protein 5;JAP3;member of PAS protein 3;member of PAS superfamily 3;MOP3;PAS domain containing 3;PAS domain-containing protein 3;PASD3;testis tissue sperm-binding protein Li 50e;TIC
Weitere Details:: The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

Versandbedingungen:: Blue Ice