![MAP4K4 antibody [4H9E7]](https://www.genetex.com/upload/website/prouct_img/normal/GTX83190/GTX83190_20170912_WB_w_23061322_545.webp)
GTX83190
MAP4K4 antibody [4H9E7]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX83190
- Zusätzliche Namen:
- mitogen-activated protein kinase kinase kinase kinase 4 , FLH21957 , HEL-S-31 , HGK , MEKKK4 , NIK
- Anwendung:
- ELISA, WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Unpurified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- Ascites, 0.03% Sodium azide.
- Immunogen:
- Purified recombinant fragment of MAP4K4 (aa400-500) expressed in E. Coli.
- Klon:
- 4H9E7
- Uniprot:
- O95819
- Synonyme:
- epididymis secretory protein Li 31;FLH21957;HEL-S-31;hepatocyte progenitor kinase-like/germinal center kinase-like kinase;HGK;HPK/GCK-like kinase HGK;MAPK/ERK kinase kinase kinase 4;MEK kinase kinase 4;MEKKK4;mitogen-activated protein kinase kinase kinase kinase 4;nck-interacting kinase;NIK;Ste20 group protein kinase HGK
- Weitere Details:
- The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice