GTX83182
DDR1 antibody [2G4E12]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX83182
- Zusätzliche Namen:
- discoidin domain receptor tyrosine kinase 1 , CAK , CD167 , DDR , EDDR1 , HGK2 , MCK10 , NEP , NTRK4 , PTK3 , PTK3A , RTK6 , TRKE
- Anwendung:
- ELISA, WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Unpurified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- Ascites, 0.03% Sodium azide.
- Immunogen:
- Purified recombinant fragment of DDR1 (aa602-681) expressed in E. Coli.
- Klon:
- 2G4E12
- Uniprot:
- Q08345
- Synonyme:
- CAK;CD167;CD167 antigen-like family member A;cell adhesion kinase;DDR;Discoidin receptor tyrosine kinase;EDDR1;epithelial discoidin domain-containing receptor 1;HGK2;mammary carcinoma kinase 10;MCK10;NEP;neuroepithelial tyrosine kinase;neurotrophic tyrosine kinase, receptor, type 4;NTRK4;Protein-tyrosine kinase 3A;protein-tyrosine kinase RTK-6;PTK3;PTK3A;PTK3A protein tyrosine kinase 3A;RTK6;TRK E;TRKE;tyrosine kinase DDR;tyrosine-protein kinase CAK
- Weitere Details:
- Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
- Versandbedingungen:
- Blue Ice