Factor VIII antibody [5E9B2]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX83141
Zusätzliche Namen:: coagulation factor VIII , AHF , DXS1253E , F8B , F8C , FVIII , HEMA
Anwendung:: ELISA, WB
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Unpurified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: Ascites, 0.03% Sodium azide.
Immunogen:: Purified recombinant fragment of F8 expressed in E. Coli.
Klon:: 5E9B2
Uniprot:: P00451
Synonyme:: AHF;antihemophilic factor;coagulation factor VIII;coagulation factor VIII A1 domain;coagulation factor VIII C2 domain;coagulation factor VIII, procoagulant component;coagulation factor VIIIc;DXS1253E;F8B;F8C;factor VIII F8B;FVIII;HEMA;Procoagulant component
Weitere Details:: This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice