Ret antibody [8D10C9]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX83058
Zusätzliche Namen:: ret proto-oncogene , CDHF12 , CDHR16 , HSCR1 , MEN2A , MEN2B , MTC1 , PTC , RET-ELE1
Anwendung:: ELISA, WB
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Unpurified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: Ascites, 0.03% Sodium azide.
Immunogen:: Purified recombinant fragment of RET (aa896-1063) expressed in E. Coli.
Klon:: 8D10C9
Uniprot:: P07949
Synonyme:: cadherin family member 12;cadherin-related family member 16;CDHF12;CDHR16;HSCR1;MEN2A;MEN2B;MTC1;proto-oncogene c-Ret;proto-oncogene tyrosine-protein kinase receptor Ret;PTC;rearranged during transfection;ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease);RET receptor tyrosine kinase;RET-ELE1
Weitere Details:: This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice