GPI antibody [1B7D7]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX83039
Zusätzliche Namen:: glucose-6-phosphate isomerase , AMF , GNPI , NLK , PGI , PHI , SA-36 , SA36
Anwendung:: ELISA, WB, IHC-P, IF, ICC
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Unpurified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human, Rat
Buffer:: Ascites, 0.03% Sodium azide.
Immunogen:: Purified recombinant fragment of human GPI expressed in E. Coli.
Klon:: 1B7D7
Uniprot:: P06744
Synonyme:: AMF;autocrine motility factor;glucose-6-phosphate isomerase;GNPI;hexose monophosphate isomerase;hexosephosphate isomerase;neuroleukin;NLK;oxoisomerase;PGI;PHI;phosphoglucose isomerase;phosphohexomutase;phosphohexose isomerase;phosphosaccharomutase;SA-36;SA36;Sperm antigen 36;sperm antigen-36
Weitere Details:: This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phophsate and fructose-6-phosphate. Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion. The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Versandbedingungen:: Blue Ice