JNK3 antibody [10E4A4]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX83031
Zusätzliche Namen:: mitogen-activated protein kinase 10 , JNK3 , JNK3A , PRKM10 , SAPK1b , p493F12 , p54bSAPK
Anwendung:: ELISA, WB, IF, ICC
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Unpurified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human, Mouse
Buffer:: Ascites, 0.03% Sodium azide.
Immunogen:: Purified recombinant fragment of human JNK3 (aa28-233) expressed in E. Coli.
Klon:: 10E4A4
Uniprot:: P53779
Synonyme:: c-Jun N-terminal kinase 3;JNK3;JNK3 alpha protein kinase;JNK3A;MAP kinase 10;MAP kinase p49 3F12;mitogen-activated protein kinase 10;p493F12;p54bSAPK;PRKM10;SAPK1b;stress activated protein kinase beta;stress-activated protein kinase 1b;stress-activated protein kinase JNK3
Weitere Details:: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice