GTX82966
PHD2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX82966
- Zusätzliche Namen:
- egl-9 family hypoxia-inducible factor 1 , AI503754 , C1orf12 , HIF-PH2 , HPH-2 , Hif-p4h-2 , ORF13 , Phd2 , SM-20
- Anwendung:
- WB, IHC-P, IF, ICC, IP
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human, Mouse
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- A synthetic peptide made to an internal portion of mouse PHD2/HIF Prolyl Hydroxylase 2 (between residues 300-400). [UniProt# Q91YE3]
- Uniprot:
- Q91YE3
- Synonyme:
- AI503754;C1orf12;egl nine homolog 1;Hif-p4h;Hif-p4h-2;HIF-PH2;HIF-prolyl hydroxylase 2;HPH-2;hypoxia-inducible factor prolyl hydroxylase 2;ORF13;Phd;Phd2;prolyl hydroxylase domain-containing protein 2;SM-2;SM-20
- Weitere Details:
- Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-402' and 'Pro-564', and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
- Versandbedingungen:
- Blue Ice