GTX82957
TGF beta Receptor 2 antibody, N-term
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX82957
- Zusätzliche Namen:
- transforming growth factor beta receptor 2 , AAT3 , FAA3 , LDS1B , LDS2 , LDS2B , MFS2 , RIIC , TAAD2 , TBR-ii , TBRII , TGFR-2 , TGFbeta-RII
- Anwendung:
- WB
- Konzentration:
- 0.5-1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 2% Sucrose, 0.09% Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to a N-terminal region of Human TGFBR2
- Uniprot:
- P37173
- Synonyme:
- AAT3;FAA3;LDS1B;LDS2;LDS2B;MFS2;RIIC;TAAD2;tbetaR-II;TBR-ii;TBRII;TGF-beta receptor type IIB;TGF-beta receptor type-2;TGF-beta type II receptor;TGFbeta-RII;TGFR-2;transforming growth factor beta receptor II;transforming growth factor beta receptor type IIC;Transforming growth factor-beta receptor type II;transforming growth factor, beta receptor II (70/80kDa);transforming growth factor, beta receptor II alpha;transforming growth factor, beta receptor II beta;transforming growth factor, beta receptor II delta;transforming growth factor, beta receptor II epsilon;transforming growth factor, beta receptor II gamma
- Weitere Details:
- The protein encoded by this gene is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Aug 2017]
- Versandbedingungen:
- Blue Ice