GTX82891
KCNQ2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX82891
- Zusätzliche Namen:
- potassium voltage-gated channel subfamily Q member 2 , BFNC , EBN , EBN1 , ENB1 , HNSPC , KCNA11 , KV7.2
- Anwendung:
- WB, IHC-P, IHC-Fr, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Immunogen:
- GST fusion protein encoding the first 70 amino acids of human KCNQ2.
- Uniprot:
- O43526
- Synonyme:
- BFNC;DEE7;EBN;EBN1;ENB1;HNSPC;KCNA11;KQT-like 2;KV7.2;neuroblastoma-specific potassium channel subunit alpha KvLQT2;potassium channel, voltage gated KQT-like subfamily Q, member 2;potassium voltage-gated channel subfamily KQT member 2;voltage-gated potassium channel subunit Kv7.2
- Weitere Details:
- The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice