![PRMT6 antibody [4G2]](https://www.genetex.com/upload/website/prouct_img/normal/GTX82806/GTX82806_20170912_WB_w_23061322_769.webp)
GTX82806
PRMT6 antibody [4G2]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX82806
- Zusätzliche Namen:
- protein arginine methyltransferase 6 , HRMT1L6
- Anwendung:
- ELISA, WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Unpurified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- Ascites, 0.03% Sodium azide.
- Immunogen:
- Purified recombinant fragment of human PRMT6 expressed in E. Coli.
- Klon:
- 4G2
- Uniprot:
- Q96LA8
- Synonyme:
- heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6;histone-arginine N-methyltransferase PRMT6;HMT1 hnRNP methyltransferase-like 6;HRMT1L6;protein arginine N-methyltransferase 6
- Weitere Details:
- The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011]
- Versandbedingungen:
- Blue Ice