TORC2 antibody [5B10]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX82754
Zusätzliche Namen:: CREB regulated transcription coactivator 2 , TORC-2 , TORC2
Anwendung:: ELISA, Flow Cytometry, WB, IHC-P, IF, ICC
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Unpurified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: Ascites, 0.03% Sodium azide.
Immunogen:: Purified recombinant fragment of human CRTC2 expressed in E. Coli.
Klon:: 5B10
Uniprot:: Q53ET0
Synonyme:: CREB-regulated transcription coactivator 2;TORC-2;TORC2;transducer of regulated cAMP response element-binding protein (CREB) 2;Transducer of regulated cAMP response element-binding protein 2
Weitere Details:: This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2010]

Versandbedingungen:: Blue Ice