GTX82618
Parkin (phospho Ser378) antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX82618
- Zusätzliche Namen:
- parkin RBR E3 ubiquitin protein ligase , AR-JP , LPRS2 , PARK2 , PDJ
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 10mM HEPES, 150mM NaCl, 0.01% BSA, 50% Glycerol, no preservatives.
- Immunogen:
- Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser378 conjugated to KLH
- Uniprot:
- O60260
- Synonyme:
- AR-JP;E3 ubiquitin-protein ligase parkin;LPRS2;PARK2;Parkin RBR E3 ubiquitin-protein ligase;Parkinson disease (autosomal recessive, juvenile) 2, parkin;parkinson juvenile disease protein 2;parkinson protein 2 E3 ubiquitin protein ligase;parkinson protein 2, E3 ubiquitin protein ligase (parkin);PDJ
- Weitere Details:
- The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice