GTX82550
FBXL11 antibody, Internal
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX82550
- Zusätzliche Namen:
- lysine demethylase 2A , CXXC8 , FBL11 , FBL7 , FBXL11 , JHDM1A , LILINA
- Anwendung:
- WB, IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- SAS Precipitated; Dialysis
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 0.09% Sodium azide.
- Immunogen:
- KLH conjugated synthetic peptide between 500-527 amino acids from the Central region of human JHDM1a/FBXL11.
- Uniprot:
- Q9Y2K7
- Synonyme:
- [Histone-H3]-lysine-36 demethylase 1A;CXXC-type zinc finger protein 8;CXXC8;F-box and leucine-rich repeat protein 11;F-box protein FBL7;F-box protein Lilina;F-box/LRR-repeat protein 11;FBL11;FBL7;FBXL11;JHDM1A;jmjC domain-containing histone demethylation protein 1A;jumonji C domain-containing histone demethylase 1A;LILINA;lysine (K)-specific demethylase 2A;lysine-specific demethylase 2A
- Weitere Details:
- This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
- Versandbedingungen:
- Blue Ice