GTX82421
STAT6 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX82421
- Zusätzliche Namen:
- signal transducer and activator of transcription 6 , D12S1644 , IL-4-STAT , STAT6B , STAT6C
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Chicken/Avian
- Reaktivitäten:
- Human
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- Immunogen Sequence: GI # 23397678, sequence 61-275 Recombinant signal transducer and activator of transcription 6
- Uniprot:
- P42226
- Synonyme:
- D12S1644;IL-4 Stat;IL-4-STAT;signal transducer and activator of transcription 6;signal transducer and activator of transcription 6, interleukin-4 induced;STAT, interleukin4-induced;STAT6B;STAT6C;transcription factor IL-4 STAT
- Weitere Details:
- Carries out a dual function: signal transduction and activation of transcription. Involved in interleukin-4 signalling. The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors. STAT family members are phosphorylated by the receptor associated kinases. and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L). which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells. expression of cell surface markers. and class switch of immunoglobulins.
- Versandbedingungen:
- Blue Ice