GTX82231
Stanniocalcin 2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX82231
- Zusätzliche Namen:
- stanniocalcin 2 , STC-2 , STCRP
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Chicken/Avian
- Reaktivitäten:
- Human, Caprine
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- Immunogen Sequence: GI # 4507267, sequence 20-302 Recombinant stanniocalcin 2
- Uniprot:
- O76061
- Synonyme:
- stanniocalcin-2;stanniocalcin-related protein;STC-2;STC-related protein;STCRP
- Weitere Details:
- Has an anti-hypocalcemic action on calcium and phosphate homeostasis. This protein is a secreted. homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport. cell metabolism. or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction. reduced bone and skeletal muscle growth. and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.
- Versandbedingungen:
- Blue Ice