GTX81638
HEXA antibody, N-term
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX81638
- Zusätzliche Namen:
- hexosaminidase subunit alpha , TSD
- Anwendung:
- Flow Cytometry, WB, IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified; Protein A Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 0.09% Sodium azide.
- Immunogen:
- KLH conjugated synthetic peptide between 142-170 amino acids from the N-terminal region of human HEXA.
- Uniprot:
- P06865
- Synonyme:
- beta-hexosaminidase subunit alpha;beta-N-acetylhexosaminidase subunit alpha;hexosaminidase A (alpha polypeptide);hexosaminidase subunit A;N-acetyl-beta-glucosaminidase subunit alpha;TSD
- Weitere Details:
- This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons, the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses, including Tay-Sachs disease (GM2-gangliosidosis type I). Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
- Versandbedingungen:
- Blue Ice